MB), Help with How well it works: Moderna's initial Phase 3 clinical data in December 2020 was similar to Pfizer-BioNTech'sat that point, both vaccines showed about 95% efficacy for prevention of COVID-19. A booster dose (0.25 mL) of Spikevax may be given at least 3 months after the second dose in See section 4. you are allergic to the active substance or any of the other ingredients of this vaccine, listed in, have previously had a severe, life-threatening allergic reaction after any other vaccine injection or after you were given Spikevax in the past, have a very weak or compromised immune system. Magen E, Mukherjee S, Bhattacharya M, Detroja R, Merzon E, Blum I, Livoff A, Shlapobersky M, Baum G, Talisman R, Cherniavsky E, Dori A, Frenkel-Morgenstern M. Vaccines (Basel). Worry over having a skin reaction should not deter you from getting a COVID-19 vaccine. Caffarelli C, Liotti L, Bianchi A, Bottau P, Caimmi S, Crisafulli G, Franceschini F, Paglialunga C, Saretta F, Mori F. Pediatr Allergy Immunol. The content on this site is intended for healthcare professionals. Adverse events after first COVID-19 vaccination in patients with autoimmune diseases. Spikevax should be administered by a trained healthcare professional. Moderna's coronavirus vaccine may cause alarming delayed side effects from its first dose among a portion of recipients. "I think this is particularly interesting because it shows that the body is mounting an immune response to the vaccine, just as it does after infection with the virus," said Freeman. Last updated 12/22 - Patient Information Leaflet for Spikevax If you miss a scheduled injection, you may not be fully protected against COVID-19. extensive swelling of the vaccinated limb, heavy menstrual bleeding (most cases appeared to be non-serious and temporary in nature). Our phase IV clinical studies alone cannot establish cause-effect relationship. The rest of this document, including information about storage and handling, can be found in the PDF. Moderna COVID-19 Vaccine Overview: What You Need to Know - Healthline Received vaccine (at least 1 dose) 312 (94.8%) Moderna 122 (39.1% . Moderna COVID Vaccine and Cellulitis staphylococcal - eHealthMe You may need to read it again. Accessed April 28, 2021. Perspective of patients with autoimmune diseases on COVID-19 vaccination.